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Protein Crystallography in Vaccine Research and Development

The use of protein X-ray crystallography for structure-based design of small-molecule drugs is well-documented and includes several notable success stories. However, it is less well-known that structural biology has emerged as a major tool for the design of novel vaccine antigens. Here, we review th...

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Detalles Bibliográficos
Autores principales: Malito, Enrico, Carfi, Andrea, Bottomley, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490488/
https://www.ncbi.nlm.nih.gov/pubmed/26068237
http://dx.doi.org/10.3390/ijms160613106