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Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells

Autophagy is an important stress response pathway responsible for the removal and recycling of damaged or redundant cytosolic constituents. Mitochondrial damage triggers selective mitochondrial autophagy (mitophagy), mediated by a variety of response factors including the Pink1/Parkin system. Using...

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Detalles Bibliográficos
Autores principales: MacVicar, Thomas D. B., Mannack, Lilith V. J. C., Lees, Robert M., Lane, Jon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490499/
https://www.ncbi.nlm.nih.gov/pubmed/26110381
http://dx.doi.org/10.3390/ijms160613356