Pharmacogenomics of Methotrexate Membrane Transport Pathway: Can Clinical Response to Methotrexate in Rheumatoid Arthritis Be Predicted?

Background: Methotrexate (MTX) is widely used for rheumatoid arthritis (RA) treatment. Single nucleotide polymorphisms (SNPs) could be used as predictors of patients’ therapeutic outcome variability. Therefore, this study aims to evaluate the influence of SNPs in genes encoding for MTX membrane tran...

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Detalles Bibliográficos
Autores principales: Lima, Aurea, Bernardes, Miguel, Azevedo, Rita, Medeiros, Rui, Seabra, Vitor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490522/
https://www.ncbi.nlm.nih.gov/pubmed/26086825
http://dx.doi.org/10.3390/ijms160613760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490522/
https://www.ncbi.nlm.nih.gov/pubmed/26086825
http://dx.doi.org/10.3390/ijms160613760

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