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Molecular snapshots of the Pex1/6 AAA+ complex in action

The peroxisomal proteins Pex1 and Pex6 form a heterohexameric type II AAA+ ATPase complex, which fuels essential protein transport across peroxisomal membranes. Mutations in either ATPase in humans can lead to severe peroxisomal disorders and early death. We present an extensive structural and bioch...

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Detalles Bibliográficos
Autores principales: Ciniawsky, Susanne, Grimm, Immanuel, Saffian, Delia, Girzalsky, Wolfgang, Erdmann, Ralf, Wendler, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490564/
https://www.ncbi.nlm.nih.gov/pubmed/26066397
http://dx.doi.org/10.1038/ncomms8331