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Molecular snapshots of the Pex1/6 AAA+ complex in action
The peroxisomal proteins Pex1 and Pex6 form a heterohexameric type II AAA+ ATPase complex, which fuels essential protein transport across peroxisomal membranes. Mutations in either ATPase in humans can lead to severe peroxisomal disorders and early death. We present an extensive structural and bioch...
Autores principales: | Ciniawsky, Susanne, Grimm, Immanuel, Saffian, Delia, Girzalsky, Wolfgang, Erdmann, Ralf, Wendler, Petra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490564/ https://www.ncbi.nlm.nih.gov/pubmed/26066397 http://dx.doi.org/10.1038/ncomms8331 |
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