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Layering genetic circuits to build a single cell, bacterial half adder

BACKGROUND: Gene regulation in biological systems is impacted by the cellular and genetic context-dependent effects of the biological parts which comprise the circuit. Here, we have sought to elucidate the limitations of engineering biology from an architectural point of view, with the aim of compil...

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Detalles Bibliográficos
Autores principales: Wong, Adison, Wang, Huijuan, Poh, Chueh Loo, Kitney, Richard I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490610/
https://www.ncbi.nlm.nih.gov/pubmed/26078033
http://dx.doi.org/10.1186/s12915-015-0146-0