Cu(II) enhances the effect of Alzheimer’s amyloid-β peptide on microglial activation

BACKGROUND: Aggregated forms of amyloid-β (Aβ) peptides are important triggers for microglial activation, which is an important pathological component in the brains of Alzheimer’s patients. Cu(II) ions are reported to be coordinated to monomeric Aβ, drive Aβ aggregation, and potentiate Aβ neurotoxic...

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Detalles Bibliográficos
Autores principales: Yu, Fengxiang, Gong, Ping, Hu, Zhuqin, Qiu, Yu, Cui, Yongyao, Gao, Xiaoling, Chen, Hongzhuan, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490619/
https://www.ncbi.nlm.nih.gov/pubmed/26104799
http://dx.doi.org/10.1186/s12974-015-0343-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490619/
https://www.ncbi.nlm.nih.gov/pubmed/26104799
http://dx.doi.org/10.1186/s12974-015-0343-3

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