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Evaluation of hGM-CSF/hTNFα surface-modified prostate cancer therapeutic vaccine in the huPBL-SCID chimeric mouse model

To validate its efficacy in the context of the human immune system, a novel therapeutic vaccine of hGM-CSF/hTNFα surface-modified PC-3 cells against human prostate cancer was evaluated in the human peripheral blood lymphocytes-severe combined immunodeficiency (huPBL-SCID) chimeric mouse model. The h...

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Detalles Bibliográficos
Autores principales: Lai, Shouhua, Huang, Zhiyong, Guo, Yunting, Cui, Yunqin, Wang, Lei, Ren, Weifeng, Ying, Furong, Gao, Hui, He, Lingxia, Zhou, Tieli, Jiang, Jiegen, Gao, Jimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490636/
https://www.ncbi.nlm.nih.gov/pubmed/26108270
http://dx.doi.org/10.1186/s13045-015-0175-8