Alternative transcripts of the SERPINA1 gene in alpha-1 antitrypsin deficiency

BACKGROUND: SERPINA1 is the gene for alpha-1 antitrypsin (AAT), an acute phase protein with anti-protease and immunoregulatory activities. Mutations in SERPINA1 gene cause AAT deficiency and predispose individuals to early-onset emphysema and liver diseases. Expression of the SERPINA1 gene is regula...

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Detalles Bibliográficos
Autores principales: Matamala, Nerea, Martínez, Maria Teresa, Lara, Beatriz, Pérez, Laura, Vázquez, Irene, Jimenez, Azucena, Barquín, Miguel, Ferrarotti, Ilaria, Blanco, Ignacio, Janciauskiene, Sabina, Martinez-Delgado, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490674/
https://www.ncbi.nlm.nih.gov/pubmed/26141700
http://dx.doi.org/10.1186/s12967-015-0585-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490674/
https://www.ncbi.nlm.nih.gov/pubmed/26141700
http://dx.doi.org/10.1186/s12967-015-0585-y

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