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Alternative transcripts of the SERPINA1 gene in alpha-1 antitrypsin deficiency

BACKGROUND: SERPINA1 is the gene for alpha-1 antitrypsin (AAT), an acute phase protein with anti-protease and immunoregulatory activities. Mutations in SERPINA1 gene cause AAT deficiency and predispose individuals to early-onset emphysema and liver diseases. Expression of the SERPINA1 gene is regula...

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Detalles Bibliográficos
Autores principales:	Matamala, Nerea, Martínez, Maria Teresa, Lara, Beatriz, Pérez, Laura, Vázquez, Irene, Jimenez, Azucena, Barquín, Miguel, Ferrarotti, Ilaria, Blanco, Ignacio, Janciauskiene, Sabina, Martinez-Delgado, Beatriz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490674/ https://www.ncbi.nlm.nih.gov/pubmed/26141700 http://dx.doi.org/10.1186/s12967-015-0585-y

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