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Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation

BACKGROUND: Potential involvement of the CCR10/CCL28 axis was recently reported in murine models of allergic asthma. If confirmed, blockade of the CCR10 receptor would represent an alternative to current asthma therapies. We evaluated the effect of a novel Protein Epitope Mimetic CCR10 antagonist, P...

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Detalles Bibliográficos
Autores principales: Daubeuf, François, Jung, Françoise, Douglas, Garry J., Chevalier, Eric, Frossard, Nelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490744/
https://www.ncbi.nlm.nih.gov/pubmed/26112287
http://dx.doi.org/10.1186/s12931-015-0231-5