Upregulation of T-type Ca(2+) channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons

BACKGROUND: Previous studies have shown that increased excitability of capsaicin-sensitive DRG neurons and thermal hyperalgesia in rats with short-term (2–4 weeks) streptozotocin-induced diabetes is mediated by upregulation of T-type Ca(2+) current. In longer–term diabetes (after the 8th week) therm...

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Detalles Bibliográficos
Autores principales: Duzhyy, Dmytro E, Viatchenko-Karpinski, Viacheslav Y, Khomula, Eugen V, Voitenko, Nana V, Belan, Pavel V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490764/
https://www.ncbi.nlm.nih.gov/pubmed/25986602
http://dx.doi.org/10.1186/s12990-015-0028-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490764/
https://www.ncbi.nlm.nih.gov/pubmed/25986602
http://dx.doi.org/10.1186/s12990-015-0028-z

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