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Upregulation of T-type Ca(2+) channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons
BACKGROUND: Previous studies have shown that increased excitability of capsaicin-sensitive DRG neurons and thermal hyperalgesia in rats with short-term (2–4 weeks) streptozotocin-induced diabetes is mediated by upregulation of T-type Ca(2+) current. In longer–term diabetes (after the 8th week) therm...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490764/ https://www.ncbi.nlm.nih.gov/pubmed/25986602 http://dx.doi.org/10.1186/s12990-015-0028-z |