Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis

Many components of the Wnt/β-catenin signaling pathway have critical functions in mammary gland development and tumor formation, yet the contribution of glycogen synthase kinase-3 (GSK-3α and GSK-3β) to mammopoiesis and oncogenesis is unclear. Here, we report that WAP-Cre-mediated deletion of GSK-3...

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Detalles Bibliográficos
Autores principales: Dembowy, J, Adissu, H A, Liu, J C, Zacksenhaus, E, Woodgett, J R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490903/
https://www.ncbi.nlm.nih.gov/pubmed/25195860
http://dx.doi.org/10.1038/onc.2014.279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490903/
https://www.ncbi.nlm.nih.gov/pubmed/25195860
http://dx.doi.org/10.1038/onc.2014.279

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