Cargando…

Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis

Many components of the Wnt/β-catenin signaling pathway have critical functions in mammary gland development and tumor formation, yet the contribution of glycogen synthase kinase-3 (GSK-3α and GSK-3β) to mammopoiesis and oncogenesis is unclear. Here, we report that WAP-Cre-mediated deletion of GSK-3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dembowy, J, Adissu, H A, Liu, J C, Zacksenhaus, E, Woodgett, J R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490903/ https://www.ncbi.nlm.nih.gov/pubmed/25195860 http://dx.doi.org/10.1038/onc.2014.279

Ejemplares similares

Interactomes of Glycogen Synthase Kinase-3 Isoforms
por: Cormier, Kevin W., et al.
Publicado: (2023)

The Effects of Glycogen Synthase Kinase-3beta in Serotonin Neurons
por: Zhou, Wenjun, et al.
Publicado: (2012)

Glycogen synthase kinase-3β promotes cyst expansion in polycystic kidney disease
por: Tao, Shixin, et al.
Publicado: (2015)

Glycogen Synthase Kinase-3
por: Crouch, Peter, et al.
Publicado: (2011)

Genetic Deficiency of Glycogen Synthase Kinase-3β Corrects Diabetes in Mouse Models of Insulin Resistance
por: Tanabe, Katsuya, et al.
Publicado: (2008)

Tissue-Specific Analysis of Glycogen Synthase Kinase-3α (GSK-3α) in Glucose Metabolism: Effect of Strain Variation
por: Patel, Satish, et al.
Publicado: (2011)

Glycogen Synthase Kinase-3β Is a Negative Regulator of Cardiomyocyte Hypertrophy
por: Haq, Syed, et al.
Publicado: (2000)

Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium
por: Kaladchibachi, Sevag A, et al.
Publicado: (2007)

Nimbolide, a neem limonoid inhibits Phosphatidyl Inositol-3 Kinase to activate Glycogen Synthase Kinase-3β in a hamster model of oral oncogenesis
por: Sophia, Josephraj, et al.
Publicado: (2016)

Myocardial stress remodelling after regional infarction is independent of glycogen synthase kinase-3 inactivation
por: Webb, Ian G., et al.
Publicado: (2010)

Mechanism of glycogen synthase inactivation and interaction with glycogenin
por: Marr, Laura, et al.
Publicado: (2022)

Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus
por: Gonzalez Malagon, Sandra G., et al.
Publicado: (2018)

Glycogen Synthase Kinase-3 Is Required for Efficient Dictyostelium Chemotaxis
por: Teo, Regina, et al.
Publicado: (2010)

Mouse Mammary Tumor Virus Molecular Biology and Oncogenesis
por: Ross, Susan R.
Publicado: (2010)

Aberrant glycogen synthase kinase 3β in the development of pancreatic cancer
por: Shimasaki, Takeo, et al.
Publicado: (2012)

Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice
por: Howard, Christiana, et al.
Publicado: (2012)

Glycogen synthase kinase 3β in tumorigenesis and oncotherapy
por: He, Rui, et al.
Publicado: (2020)

Light and Electron Microscopy Study of Glycogen Synthase Kinase-3β in the Mouse Brain
por: Perez-Costas, Emma, et al.
Publicado: (2010)

Pharmacological Inhibition of Glycogen Synthase Kinase 3 Regulates T Cell Development In Vitro
por: Schroeder, Jan-Hendrik, et al.
Publicado: (2013)

Antidiabetic and vasoprotective activity of lithium: Role of glycogen synthase kinase-3
por: Kanzariya, Nilesh R., et al.
Publicado: (2011)

Glycogen Synthase Kinase-3 in the Etiology and Treatment of Mood Disorders
por: Jope, Richard Scott
Publicado: (2011)

Glycogen Synthase Kinase-3 is an Intermediate Modulator of Serotonin Neurotransmission
por: Polter, Abigail M., et al.
Publicado: (2011)

Glycogen Synthase Kinase 3β in Cancer Biology and Treatment
por: Domoto, Takahiro, et al.
Publicado: (2020)

Glycogen Synthase Kinase 3: Ion Channels, Plasticity, and Diseases
por: Marosi, Mate, et al.
Publicado: (2022)

The role of glycogen synthase kinase 3 beta in neurodegenerative diseases
por: Yu, Honglu, et al.
Publicado: (2023)

Inactivation of glycogen synthase kinase-3α is required for mitochondria-mediated apoptotic germ cell phagocytosis in Sertoli cells
por: Gong, Yabin, et al.
Publicado: (2018)

Effects of Visfatin on Intracellular Mechanics and Catabolism in Human Primary Chondrocytes through Glycogen Synthase Kinase 3β Inactivation
por: Chang, Shun-Fu, et al.
Publicado: (2021)

Functional inactivation of Plasmodium falciparum glycogen synthase kinase GSK3 modulates erythrocyte invasion and blocks gametocyte maturation
por: Alder, Arne, et al.
Publicado: (2022)

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD
por: Ngkelo, Anta, et al.
Publicado: (2015)

Glycogen Synthase Kinase-3 (GSK-3)-Targeted Therapy and Imaging
por: Pandey, Mukesh K., et al.
Publicado: (2016)

Correction: Pharmacological Inhibition of Glycogen Synthase Kinase 3 Regulates T Cell Development In Vitro
por: Schroeder, Jan-Hendrik, et al.
Publicado: (2013)

Differential Roles of Glycogen Synthase Kinase 3 Subtypes Alpha and Beta in Cortical Development
por: Ma, Yan-xia, et al.
Publicado: (2017)

Regenerative potential of targeting glycogen synthase kinase-3 signaling in neural tissues
por: Jung, Eui-Man, et al.
Publicado: (2015)

Glycogen Synthase Kinase 3β: A True Foe in Pancreatic Cancer
por: Elmadbouh, Omer H. M., et al.
Publicado: (2022)

In Silico Approaches to Developing Novel Glycogen Synthase Kinase 3β (GSK-3β)
por: Goyal, Shuchi, et al.
Publicado: (2023)

Allosteric Regulation of Glycogen Synthase Kinase 3β: A Theoretical Study
por: Buch, Idit, et al.
Publicado: (2010)

Glycogen synthase kinase 3β represses MYOGENIN function in alveolar rhabdomyosarcoma
por: Dionyssiou, M G, et al.
Publicado: (2014)

Glycogen Synthase Kinase 3 (GSK3) Inhibitor, SB-216763, Promotes Pluripotency in Mouse Embryonic Stem Cells
por: Kirby, Leslie A., et al.
Publicado: (2012)

Functional Implications of Glycogen Synthase Kinase-3-Mediated Tau Phosphorylation
por: Hanger, Diane P., et al.
Publicado: (2011)

Regulation by Glycogen Synthase Kinase-3 of Inflammation and T Cells in CNS Diseases
por: Beurel, Eléonore
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ulo2mc4m42hs7eshnref6kubjn