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Metabolomic Identification of a Novel Pathway of Blood Pressure Regulation Involving Hexadecanedioate

High blood pressure is a major contributor to the global burden of disease and discovering novel causal pathways of blood pressure regulation has been challenging. We tested blood pressure associations with 280 fasting blood metabolites in 3980 TwinsUK females. Survival analysis for all-cause mortal...

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Detalles Bibliográficos
Autores principales: Menni, Cristina, Graham, Delyth, Kastenmüller, Gabi, Alharbi, Nora H.J., Alsanosi, Safaa Md, McBride, Martin, Mangino, Massimo, Titcombe, Philip, Shin, So-Youn, Psatha, Maria, Geisendorfer, Thomas, Huber, Anja, Peters, Annette, Wang-Sattler, Rui, Xu, Tao, Brosnan, Mary Julia, Trimmer, Jeff, Reichel, Christian, Mohney, Robert P., Soranzo, Nicole, Edwards, Mark H., Cooper, Cyrus, Church, Alistair C., Suhre, Karsten, Gieger, Christian, Dominiczak, Anna F., Spector, Tim D., Padmanabhan, Sandosh, Valdes, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott, Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490909/
https://www.ncbi.nlm.nih.gov/pubmed/26034203
http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05544