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Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies
Most pathogens initiate their infections at the human mucosal surface. Therefore, mucosal vaccination, especially through oral or intranasal administration routes, is highly desired for infectious diseases. Meanwhile, protein-based antigens provide a safer alternative to the whole pathogen or DNA ba...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491048/ https://www.ncbi.nlm.nih.gov/pubmed/25944045 http://dx.doi.org/10.1007/s13238-015-0164-2 |