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Eliminate mitochondrial diseases by gene editing in germ-line cells and embryos

Nuclease-based gene editing technologies have opened up opportunities for correcting human genetic diseases. For the first time, scientists achieved targeted gene editing of mitochondrial DNA in mouse oocytes fused with patient cells. This fascinating progression may encourage the development of nov...

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Detalles Bibliográficos
Autores principales: Wang, Si, Yi, Fei, Qu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491053/
https://www.ncbi.nlm.nih.gov/pubmed/26081469
http://dx.doi.org/10.1007/s13238-015-0177-x