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Synthesis and anticonvulsant activity of new N-phenyl-2-(4-phenylpiperazin-1-yl)acetamide derivatives

Twenty-two new N-phenyl-2-(4-phenylpiperazin-1-yl)acetamide derivatives have been synthesized and evaluated for their anticonvulsant activity in animal models of epilepsy. These molecules have been designed as analogs of previously obtained anticonvulsant active pyrrolidine-2,5-diones in which heter...

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Detalles Bibliográficos
Autores principales: Kamiński, Krzysztof, Wiklik, Beata, Obniska, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491109/
https://www.ncbi.nlm.nih.gov/pubmed/26167103
http://dx.doi.org/10.1007/s00044-015-1360-6