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Engineering targeted chromosomal amplifications in human breast epithelial cells

Chromosomal amplifications are among the most common genetic alterations found in human cancers. However, experimental systems to study the processes that lead to specific, recurrent amplification events in human cancers are lacking. Moreover, some common amplifications, such as that at 8p11-12 in b...

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Detalles Bibliográficos
Autores principales: Springer, Simeon, Yi, Kyung H., Park, Jeenah, Rajpurohit, Anandita, Price, Amanda J., Lauring, Josh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491111/
https://www.ncbi.nlm.nih.gov/pubmed/26099605
http://dx.doi.org/10.1007/s10549-015-3468-2