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Engineering targeted chromosomal amplifications in human breast epithelial cells
Chromosomal amplifications are among the most common genetic alterations found in human cancers. However, experimental systems to study the processes that lead to specific, recurrent amplification events in human cancers are lacking. Moreover, some common amplifications, such as that at 8p11-12 in b...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491111/ https://www.ncbi.nlm.nih.gov/pubmed/26099605 http://dx.doi.org/10.1007/s10549-015-3468-2 |