Grb2 monomer–dimer equilibrium determines normal versus oncogenic function

The adaptor protein growth factor receptor-bound protein 2 (Grb2) is ubiquitously expressed in eukaryotic cells and involved in a multitude of intracellular protein interactions. Grb2 plays a pivotal role in tyrosine kinase-mediated signal transduction including linking receptor tyrosine kinases to...

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Detalles Bibliográficos
Autores principales: Ahmed, Zamal, Timsah, Zahra, Suen, Kin M., Cook, Nathan P., Lee, Gilbert R., Lin, Chi-Chuan, Gagea, Mihai, Marti, Angel A., Ladbury, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491180/
https://www.ncbi.nlm.nih.gov/pubmed/26103942
http://dx.doi.org/10.1038/ncomms8354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491180/
https://www.ncbi.nlm.nih.gov/pubmed/26103942
http://dx.doi.org/10.1038/ncomms8354

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