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Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate

Although neural c-Jun is essential for successful peripheral nerve regeneration, the cellular basis of this effect and the impact of c-Jun activation are incompletely understood. In the current study, we explored the effects of neuron-selective c-Jun deletion, substitution of serine 63 and 73 phosph...

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Detalles Bibliográficos
Autores principales: Ruff, Crystal A, Staak, Nils, Patodia, Smriti, Kaswich, Mark, Rocha-Ferreira, Eridan, Da Costa, Clive, Brecht, Stephan, Makwana, Milan, Fontana, Xavier, Hristova, Mariya, Rumajogee, Prakasham, Galiano, Matthias, Bohatschek, Marion, Herdegen, Thomas, Behrens, Axel, Raivich, Gennadij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491308/
https://www.ncbi.nlm.nih.gov/pubmed/22372722
http://dx.doi.org/10.1111/j.1471-4159.2012.07706.x