Targeting the plasma membrane of neoplastic cells through alkylation: a novel approach to cancer chemotherapy

Background Although DNA-directed alkylating agents and related compounds have been a mainstay in chemotherapeutic protocols due to their ability to readily interfere with the rapid mitotic progression of malignant cells, their clinical utility is limited by DNA repair mechanisms and immunosuppressio...

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Detalles Bibliográficos
Autores principales: Trendowski, Matthew, Fondy, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491345/
https://www.ncbi.nlm.nih.gov/pubmed/26095786
http://dx.doi.org/10.1007/s10637-015-0263-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491345/
https://www.ncbi.nlm.nih.gov/pubmed/26095786
http://dx.doi.org/10.1007/s10637-015-0263-1

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