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Changes of Proteases, Antiproteases, and Pathogens in Cystic Fibrosis Patients' Upper and Lower Airways after IV-Antibiotic Therapy

Background. In cystic fibrosis (CF) the upper (UAW) and lower airways (LAW) are reservoirs for pathogens like Pseudomonas aeruginosa. The consecutive hosts' release of proteolytic enzymes contributes to inflammation and progressive pulmonary destruction. Objectives were to assess dynamics of pr...

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Detalles Bibliográficos
Autores principales: Müller, Ulrike, Hentschel, Julia, Janhsen, Wibke K., Hünniger, Kerstin, Hipler, Uta-Christina, Sonnemann, Jürgen, Pfister, Wolfgang, Böer, Klas, Lehmann, Thomas, Mainz, Jochen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491395/
https://www.ncbi.nlm.nih.gov/pubmed/26185365
http://dx.doi.org/10.1155/2015/626530