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Changes of Proteases, Antiproteases, and Pathogens in Cystic Fibrosis Patients' Upper and Lower Airways after IV-Antibiotic Therapy
Background. In cystic fibrosis (CF) the upper (UAW) and lower airways (LAW) are reservoirs for pathogens like Pseudomonas aeruginosa. The consecutive hosts' release of proteolytic enzymes contributes to inflammation and progressive pulmonary destruction. Objectives were to assess dynamics of pr...
Autores principales: | Müller, Ulrike, Hentschel, Julia, Janhsen, Wibke K., Hünniger, Kerstin, Hipler, Uta-Christina, Sonnemann, Jürgen, Pfister, Wolfgang, Böer, Klas, Lehmann, Thomas, Mainz, Jochen G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491395/ https://www.ncbi.nlm.nih.gov/pubmed/26185365 http://dx.doi.org/10.1155/2015/626530 |
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