The Pathogenicity of Anti-β2GP1-IgG Autoantibodies Depends on Fc Glycosylation

To analyze the glycosylation of anti-β2GP1, we investigated purified IgG from healthy children, patients with APS, and asymptomatic adult carriers of antiphospholipid antibodies. We observed that in the sera of healthy children and of patients with APS, IgG3 and IgG2 were predominant, respectively....

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Detalles Bibliográficos
Autores principales: Fickentscher, Christoph, Magorivska, Iryna, Janko, Christina, Biermann, Mona, Bilyy, Rostyslav, Nalli, Cecilia, Tincani, Angela, Medeghini, Veronica, Meini, Antonella, Nimmerjahn, Falk, Schett, Georg, Muñoz, Luis E., Andreoli, Laura, Herrmann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491572/
https://www.ncbi.nlm.nih.gov/pubmed/26185769
http://dx.doi.org/10.1155/2015/638129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491572/
https://www.ncbi.nlm.nih.gov/pubmed/26185769
http://dx.doi.org/10.1155/2015/638129

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