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Rap1 is indispensable for TRF2 function in etoposide-induced DNA damage response in gastric cancer cell line

The telomeric protein TRF2, involving in telomeric and extratelomeric DNA damage response, has been previously reported to facilitate multidrug resistance (MDR) in gastric cancer cells by interfering ATM-dependent DNA damage response induced by anticancer drugs. Rap1 is the TRF2-interacting protein...

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Detalles Bibliográficos
Autores principales: Li, X, Liu, W, Wang, H, Yang, L, Li, Y, Wen, H, Ning, H, Wang, J, Zhang, L, Li, J, Fan, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491608/
https://www.ncbi.nlm.nih.gov/pubmed/25821946
http://dx.doi.org/10.1038/oncsis.2015.1