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Subthalamic deep brain stimulation reduces pathological information transmission to the thalamus in a rat model of parkinsonism

The degeneration of dopaminergic neurons in the substantia nigra pars compacta leads to parkinsonian motor symptoms via changes in electrophysiological activity throughout the basal ganglia. High-frequency deep brain stimulation (DBS) partially treats these symptoms, but the mechanisms are unclear....

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Detalles Bibliográficos
Autores principales: Anderson, Collin J., Sheppard, Daylan T., Huynh, Rachel, Anderson, Daria Nesterovich, Polar, Christian A., Dorval, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491629/
https://www.ncbi.nlm.nih.gov/pubmed/26217192
http://dx.doi.org/10.3389/fncir.2015.00031