Effect of the Compaction and the Size of DNA on the Nuclear Transfer Efficiency after Microinjection in Synchronized Cells

The nuclear transfer process is one of the critical rate-limiting processes in transgene expression. In the present study, we report on the effect of compaction and the size of the DNA molecule on nuclear transfer efficiency by microinjection. A DNA/protamine complex- or variously-sized naked DNA mo...

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Detalles Bibliográficos
Autores principales: Akita, Hidetaka, Kurihara, Dai, Schmeer, Marco, Schleef, Martin, Harashima, Hideyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491651/
https://www.ncbi.nlm.nih.gov/pubmed/26066769
http://dx.doi.org/10.3390/pharmaceutics7020064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491651/
https://www.ncbi.nlm.nih.gov/pubmed/26066769
http://dx.doi.org/10.3390/pharmaceutics7020064

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