Microwave-Assisted Synthesis of a MK2 Inhibitor by Suzuki-Miyaura Coupling for Study in Werner Syndrome Cells

Microwave-assisted Suzuki-Miyaura cross-coupling reactions have been employed towards the synthesis of three different MAPKAPK2 (MK2) inhibitors to study accelerated aging in Werner syndrome (WS) cells, including the cross-coupling of a 2-chloroquinoline with a 3-pyridinylboronic acid, the coupling...

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Detalles Bibliográficos
Autores principales: Bagley, Mark C., Baashen, Mohammed, Chuckowree, Irina, Dwyer, Jessica E., Kipling, David, Davis, Terence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491660/
https://www.ncbi.nlm.nih.gov/pubmed/26046488
http://dx.doi.org/10.3390/ph8020257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491660/
https://www.ncbi.nlm.nih.gov/pubmed/26046488
http://dx.doi.org/10.3390/ph8020257

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