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cMET in NSCLC: Can We Cut off the Head of the Hydra? From the Pathway to the Resistance

In the last decade, the tyrosine kinase receptor cMET, together with its ligand hepatocyte growth factor (HGF), has become a target in non-small cell lung cancer (NSCLC). Signalization via cMET stimulates several oncological processes amongst which are cell motility, invasion and metastasis. It also...

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Detalles Bibliográficos
Autores principales: Van Der Steen, Nele, Pauwels, Patrick, Gil-Bazo, Ignacio, Castañon, Eduardo, Raez, Luis, Cappuzzo, Federico, Rolfo, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491670/
https://www.ncbi.nlm.nih.gov/pubmed/25815459
http://dx.doi.org/10.3390/cancers7020556