New Variants of Tomato Thymidine Kinase 1 Selected for Increased Sensitivity of E. coli KY895 towards Azidothymidine

Nucleoside analogues (NA) are prodrugs that are phosphorylated by deoxyribonucleoside kinases (dNKs) as the first step towards a compound toxic to the cell. During the last 20 years, research around dNKs has gone into new organisms other than mammals and viruses. Newly discovered dNKs have been test...

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Detalles Bibliográficos
Autores principales: Slot Christiansen, Louise, Egeblad, Louise, Munch-Petersen, Birgitte, Piškur, Jure, Knecht, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491694/
https://www.ncbi.nlm.nih.gov/pubmed/26061968
http://dx.doi.org/10.3390/cancers7020819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491694/
https://www.ncbi.nlm.nih.gov/pubmed/26061968
http://dx.doi.org/10.3390/cancers7020819

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