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New Variants of Tomato Thymidine Kinase 1 Selected for Increased Sensitivity of E. coli KY895 towards Azidothymidine
Nucleoside analogues (NA) are prodrugs that are phosphorylated by deoxyribonucleoside kinases (dNKs) as the first step towards a compound toxic to the cell. During the last 20 years, research around dNKs has gone into new organisms other than mammals and viruses. Newly discovered dNKs have been test...
Autores principales: | Slot Christiansen, Louise, Egeblad, Louise, Munch-Petersen, Birgitte, Piškur, Jure, Knecht, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491694/ https://www.ncbi.nlm.nih.gov/pubmed/26061968 http://dx.doi.org/10.3390/cancers7020819 |
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