Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity

The oncogenic BRAF(V600E) mutation is common in melanomas as well as moles. The roles that this mutation plays in the early events in the development of melanoma are poorly understood. This study demonstrates that expression of BRAF(V600E) is not only clastogenic, but synergizes for clastogenesis ca...

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Detalles Bibliográficos
Autores principales: Simpson, Dennis A., Lemonie, Nathalay, Morgan, David S., Gaddameedhi, Shobhan, Kaufmann, William K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491700/
https://www.ncbi.nlm.nih.gov/pubmed/26091525
http://dx.doi.org/10.3390/cancers7020825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491700/
https://www.ncbi.nlm.nih.gov/pubmed/26091525
http://dx.doi.org/10.3390/cancers7020825

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