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Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity
The oncogenic BRAF(V600E) mutation is common in melanomas as well as moles. The roles that this mutation plays in the early events in the development of melanoma are poorly understood. This study demonstrates that expression of BRAF(V600E) is not only clastogenic, but synergizes for clastogenesis ca...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491700/ https://www.ncbi.nlm.nih.gov/pubmed/26091525 http://dx.doi.org/10.3390/cancers7020825 |