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Synergistic activity of polarised osteoblasts inside condensations cause their differentiation

Condensation of pre-osteogenic, or pre-chondrogenic, cells is the first of a series of processes that initiate skeletal development. We present a validated, novel, three-dimensional agent-based model of in vitro intramembranous osteogenic condensation. The model, informed by system heterogeneity and...

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Detalles Bibliográficos
Autores principales: Kaul, Himanshu, Hall, Brian K., Newby, Chris, Ventikos, Yiannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491713/
https://www.ncbi.nlm.nih.gov/pubmed/26146365
http://dx.doi.org/10.1038/srep11838