Specificity and catalysis hardwired at the RNA–protein interface in a translational proofreading enzyme

Proofreading modules of aminoacyl-tRNA synthetases are responsible for enforcing a high fidelity during translation of the genetic code. They use strategically positioned side chains for specifically targeting incorrect aminoacyl-tRNAs. Here, we show that a unique proofreading module possessing a D-...

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Detalles Bibliográficos
Autores principales: Ahmad, Sadeem, Muthukumar, Sowndarya, Kuncha, Santosh Kumar, Routh, Satya Brata, Yerabham, Antony S.K., Hussain, Tanweer, Kamarthapu, Venu, Kruparani, Shobha P, Sankaranarayanan, Rajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491819/
https://www.ncbi.nlm.nih.gov/pubmed/26113036
http://dx.doi.org/10.1038/ncomms8552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491819/
https://www.ncbi.nlm.nih.gov/pubmed/26113036
http://dx.doi.org/10.1038/ncomms8552

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