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Anti-HMGB1 antibody reduces weight gain in mice fed a high-fat diet

Insulin resistance in obesity is believed to be propagated by adipose tissue and liver inflammation. HMGB1 is a multifunctional protein that is pro-inflammatory when released from cells. It has been previously demonstrated that anti-HMGB1 antibody reduces atherosclerotic lesion pro-inflammatory cell...

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Detalles Bibliográficos
Autores principales: Montes, V N, Subramanian, S, Goodspeed, L, Wang, S A, Omer, M, Bobik, A, Teshigawara, K, Nishibori, M, Chait, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491852/
https://www.ncbi.nlm.nih.gov/pubmed/26075638
http://dx.doi.org/10.1038/nutd.2015.11