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Anti-HMGB1 antibody reduces weight gain in mice fed a high-fat diet
Insulin resistance in obesity is believed to be propagated by adipose tissue and liver inflammation. HMGB1 is a multifunctional protein that is pro-inflammatory when released from cells. It has been previously demonstrated that anti-HMGB1 antibody reduces atherosclerotic lesion pro-inflammatory cell...
Autores principales: | Montes, V N, Subramanian, S, Goodspeed, L, Wang, S A, Omer, M, Bobik, A, Teshigawara, K, Nishibori, M, Chait, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491852/ https://www.ncbi.nlm.nih.gov/pubmed/26075638 http://dx.doi.org/10.1038/nutd.2015.11 |
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