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Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression

BACKGROUND: Selective maintenance of genomic epigenetic imprints during pre-implantation development is required for parental origin-specific expression of imprinted genes. The Kruppel-like zinc finger protein ZFP57 acts as a factor necessary for maintaining the DNA methylation memory at multiple im...

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Detalles Bibliográficos
Autores principales: Strogantsev, Ruslan, Krueger, Felix, Yamazawa, Kazuki, Shi, Hui, Gould, Poppy, Goldman-Roberts, Megan, McEwen, Kirsten, Sun, Bowen, Pedersen, Roger, Ferguson-Smith, Anne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491874/
https://www.ncbi.nlm.nih.gov/pubmed/26025256
http://dx.doi.org/10.1186/s13059-015-0672-7