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Software for the analysis and visualization of deep mutational scanning data

BACKGROUND: Deep mutational scanning is a technique to estimate the impacts of mutations on a gene by using deep sequencing to count mutations in a library of variants before and after imposing a functional selection. The impacts of mutations must be inferred from changes in their counts after selec...

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Detalles Bibliográficos
Autor principal: Bloom, Jesse D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491876/
https://www.ncbi.nlm.nih.gov/pubmed/25990960
http://dx.doi.org/10.1186/s12859-015-0590-4