Deoxycytidine production by a metabolically engineered Escherichia coli strain

BACKGROUND: Rational engineering studies for deoxycytidine production were initiated due to low intracellular levels and tight regulation. To achieve high-level production of deoxycytidine, a useful precursor of decitabine, genes related to feed-back inhibition as well as the biosynthetic pathway we...

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Detalles Bibliográficos
Autores principales: Kim, Jin-Sook, Koo, Bong-Seong, Hyun, Hyung-Hwan, Lee, Hyeon-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491880/
https://www.ncbi.nlm.nih.gov/pubmed/26148515
http://dx.doi.org/10.1186/s12934-015-0291-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491880/
https://www.ncbi.nlm.nih.gov/pubmed/26148515
http://dx.doi.org/10.1186/s12934-015-0291-8

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