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Deoxycytidine production by a metabolically engineered Escherichia coli strain
BACKGROUND: Rational engineering studies for deoxycytidine production were initiated due to low intracellular levels and tight regulation. To achieve high-level production of deoxycytidine, a useful precursor of decitabine, genes related to feed-back inhibition as well as the biosynthetic pathway we...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491880/ https://www.ncbi.nlm.nih.gov/pubmed/26148515 http://dx.doi.org/10.1186/s12934-015-0291-8 |