Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function

Key transcription factors control the gene expression program in mature pancreatic β-cells, but their integration into regulatory networks is little understood. Here, we show that Insm1, Neurod1 and Foxa2 directly interact and together bind regulatory sequences in the genome of mature pancreatic β-c...

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Detalles Bibliográficos
Autores principales: Jia, Shiqi, Ivanov, Andranik, Blasevic, Dinko, Müller, Thomas, Purfürst, Bettina, Sun, Wei, Chen, Wei, Poy, Matthew N, Rajewsky, Nikolaus, Birchmeier, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492000/
https://www.ncbi.nlm.nih.gov/pubmed/25828096
http://dx.doi.org/10.15252/embj.201490819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492000/
https://www.ncbi.nlm.nih.gov/pubmed/25828096
http://dx.doi.org/10.15252/embj.201490819

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