HTJoinSolver: Human immunoglobulin VDJ partitioning using approximate dynamic programming constrained by conserved motifs

BACKGROUND: Partitioning the human immunoglobulin variable region into variable (V), diversity (D), and joining (J) segments is a common sequence analysis step. We introduce a novel approximate dynamic programming method that uses conserved immunoglobulin gene motifs to improve performance of aligni...

Descripción completa

Detalles Bibliográficos
Autores principales: Russ, Daniel E, Ho, Kwan-Yuet, Longo, Nancy S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492005/
https://www.ncbi.nlm.nih.gov/pubmed/26001675
http://dx.doi.org/10.1186/s12859-015-0589-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492005/
https://www.ncbi.nlm.nih.gov/pubmed/26001675
http://dx.doi.org/10.1186/s12859-015-0589-x

Ejemplares similares