FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans

BACKGROUND: Periodontitis is a bacteria-driven inflammatory bone loss disease. Previous studies showed that the oral pathogen Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) stimulated the generation of sphingosine 1 phosphate (S1P). In addition, S1P signaling regulated the migratio...

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Detalles Bibliográficos
Autores principales: Yu, Hong, Herbert, Bethany A., Valerio, Michael, Yarborough, Leigh, Hsu, Li-Chien, Argraves, Kelley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492085/
https://www.ncbi.nlm.nih.gov/pubmed/26138336
http://dx.doi.org/10.1186/s12944-015-0057-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492085/
https://www.ncbi.nlm.nih.gov/pubmed/26138336
http://dx.doi.org/10.1186/s12944-015-0057-7

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