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FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans

BACKGROUND: Periodontitis is a bacteria-driven inflammatory bone loss disease. Previous studies showed that the oral pathogen Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) stimulated the generation of sphingosine 1 phosphate (S1P). In addition, S1P signaling regulated the migratio...

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Detalles Bibliográficos
Autores principales:	Yu, Hong, Herbert, Bethany A., Valerio, Michael, Yarborough, Leigh, Hsu, Li-Chien, Argraves, Kelley M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492085/ https://www.ncbi.nlm.nih.gov/pubmed/26138336 http://dx.doi.org/10.1186/s12944-015-0057-7

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