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Arterial endothelial methylome: differential DNA methylation in athero-susceptible disturbed flow regions in vivo

BACKGROUND: Atherosclerosis is a heterogeneously distributed disease of arteries in which the endothelium plays an important central role. Spatial transcriptome profiling of endothelium in pre-lesional arteries has demonstrated differential phenotypes primed for athero-susceptibility at hemodynamic...

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Detalles Bibliográficos
Autores principales: Jiang, Yi-Zhou, Manduchi, Elisabetta, Stoeckert, Christian J., Davies, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492093/
https://www.ncbi.nlm.nih.gov/pubmed/26148682
http://dx.doi.org/10.1186/s12864-015-1656-4