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Probing long-range interactions by extracting free energies from genome-wide chromosome conformation capture data
BACKGROUND: A variety of DNA binding proteins are involved in regulating and shaping the packing of chromatin. They aid the formation of loops in the DNA that function to isolate different structural domains. A recent experimental technique, Hi-C, provides a method for determining the frequency of s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492175/ https://www.ncbi.nlm.nih.gov/pubmed/26001583 http://dx.doi.org/10.1186/s12859-015-0584-2 |