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Probing long-range interactions by extracting free energies from genome-wide chromosome conformation capture data

BACKGROUND: A variety of DNA binding proteins are involved in regulating and shaping the packing of chromatin. They aid the formation of loops in the DNA that function to isolate different structural domains. A recent experimental technique, Hi-C, provides a method for determining the frequency of s...

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Detalles Bibliográficos
Autores principales:	Saberi, Saeed, Farré, Pau, Cuvier, Olivier, Emberly, Eldon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492175/ https://www.ncbi.nlm.nih.gov/pubmed/26001583 http://dx.doi.org/10.1186/s12859-015-0584-2

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